Thermoelectric materials have gained myriad attentions as alternative materials for energy harvesting, due to it can convert gradient temperature to electricity especially in the range of middle temperature[1]. The efficiency of thermoelectric materials are defined by term figure of merit (ZT), which is formulated by: ZT = S2σT/к, where S is the Seebeck coefficient or thermopower (V/K), σ is the electrical conductivity (S/m), T is the absolute temperature (K), and к is the thermal conductivity (W/mK). Here, I concern to construct the system which can measure the Seebeck coefficient of materials. In my current research I have already measured the Seebeck coefficient of Nickel plate and organic compound (pentacene). Due to the high mobility of pentacene (up to 3 cm2/Vs), it is potential to explore and develop further.